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. Author manuscript; available in PMC: 2016 Oct 15.
Published in final edited form as: Dev Biol. 2015 Sep 16;406(2):186–195. doi: 10.1016/j.ydbio.2015.08.021

Figure 6. Ephrin-B2-independent perturbation of vascular function results in failed neural crest development.

Figure 6

(A–F) Whole mount immunostaining against CD31 and Sox10 in E9.5 embryos of indicated genotypes reveals dysmorphic branchial arches (white arrowheads) and greatly diminished trigeminal NCC streams (white arrows). (G,H) Whole mount in situ hybridization for Sox10 reveals reduced and disorganized segmental TNCC migration in Ephb4null (G) and Ncx1null (H) embryos. Asterisk marks the forelimb bud. Scale bars: 200μm.