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. 2015 Nov 9;61(Suppl 5):S404–S409. doi: 10.1093/cid/civ595

Figure 3.

Figure 3.

Immunogenicity of different molecular sizes of group A conjugate recovered from Sephacryl S-400 chromatography (see Figure 4) by enzyme-linked immunosorbent assay (ELISA) (A) and by serum bactericidal assay (SBA) (B). The ELISA antibody units were determined in comparison to a reference serum assigned 3200 units/mL. Geometric mean SBA titers are shown (B) for sera from 10 mice using rabbit (R) complement against group A strain F8238 and using human (H) complement using group A strain Z1092. The rabbit and human complement SBAs were performed in different laboratories [26]. Abbreviations: IgG, immunoglobulin G; Mn A PS, group A meningococcal polysaccharide.