Table 3.
Distribution of patients by GI events before and after OP diagnosis
| Cohort | Pre-OP diagnosis of GI events, N (%) | Post-OP diagnosis GI events, N (%)
|
Total | |
|---|---|---|---|---|
| No | Yes | |||
| All patients (N=126,188) | No | 61,100 (82.9) | 12,577 (17.1) | 73,677 (58.4) |
| Yes | 29,831 (56.8) | 22,680 (43.2) | 52,511 (41.6) | |
| Total | 90,931 (72.1) | 35,257 (27.9) | 126,188 (100.0) | |
| Patients who did not initiate | No | 35,767 (67.2) | 17,497 (32.9) | 53,264 (58.5) |
| OP treatment (N=91,021) | Yes | 11,614 (30.8) | 26,143 (69.2) | 37,757 (41.5) |
| Total | 47,381 (52.1) | 43,640 (47.9) | 91,021 (100.0) | |
| Patients initiated on BIS (N=27,267) | No | 14,558 (89.0) | 1,803 (11.0) | 16,361 (60.0) |
| Yes | 7,554 (69.3) | 3,352 (30.7) | 10,906 (40.0) | |
| Total | 22,112 (81.1) | 5,155 (18.9) | 27,267 (100.0) | |
| Patients initiated on non-BIS (N=7,900) | No | 3,389 (83.6) | 663 (16.4) | 4,052 (51.3) |
| Yes | 2,379 (61.8) | 1,469 (38.2) | 3,848 (48.7) | |
| Total | 5,768 (73.0) | 2,132 (27.0) | 7,900 (100.0) | |
Abbreviations: GI, gastrointestinal; OP, osteoporosis; N, total number; BIS, bisphosphonates.