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. 2015 Nov 9;5:62. doi: 10.1186/s13550-015-0142-y

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© Bison et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 4 — Graphs showing SSTR expression of H69 tumours treated with temozolomide (TMZ) and tumour uptake of ¹¹¹In-octreotide. a Quantification of somatostatin receptor (SSTR) density in frozen sections of H69 tumours as determined by ¹¹¹In-octreotide in vitro autoradiography. The amount of radioactivity is expressed in density light units (DLU) per square millimetre. SSTR expression was quantified at day 0, day 14 (1 day after TMZ treatment), and day 28 when tumours reached a minimal volume after TMZ treatment. Three tumours/day were examined. b Based on SPECT images, the average tumour concentration of ¹¹¹In-octreotide was determined 24 h after administration. Mice were treated with TMZ from day 0 until day 13