Table 2.
Treatment schedule and number of mice for each group
| Group | Treatment | Number of mice | |
|---|---|---|---|
| 177Lu-TATE | TMZ | ||
| Control | – | Placebo | 5 |
| 1: PRRT single | 30 MBq day 0 | Placebo | 8 |
| 2: PRRT double | 30 MBq day 0 | Placebo | 8 |
| 3: TMZ | – | 50 mg/kg for 14 days from day 0 | 8 |
| 4: PRRT + TMZ at day 14 | 30 MBq day 0 | 50 mg/kg for 14 days from day 14 | 8 |
| 5: PRRT + TMZ | 30 MBq day 0 | 50 mg/kg for 14 days from day 0 | 8 |
| 6: TMZ + PRRT at day 14 | 30 MBq day 14 | 50 mg/kg for 14 days from day 0 | 10 |
177 Lu-TATE lutetium-177-labelled octreotate, TMZ temozolomide, PRRT peptide receptor radionuclide therapy