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. 2015 Nov 4;10:6905–6918. doi: 10.2147/IJN.S91316

Figure 4.

Figure 4

TEM and AFM images showing the nanostructure of the lyophilized solids of AERL in water and rat plasma.

Notes: (A) TEM image of nanoparticles of AERL in water, 4.5–63.6 nm in diameter (concentration, 1.0 mg/mL). (B) TEM image of nanoparticles of AERL in water, 32.9–180.8 nm in diameter (concentration, 0.5 mg/mL). (C) TEM image of nanoparticles of AERL in water, 38.9–227.8 nm in diameter (concentration, 0.25 mg/mL). (D) TEM image of nanoparticles of AERL in water, 45.7–234.3 nm in diameter (concentration, 0.12 mg/mL). (E) AFM image of nanoparticles of AERL in rat plasma, 53–159 nm in diameter (concentration, 0.5 mg/mL). Two red arrowheads indicate the diameter of the nanoparticle. (F) AFM image of nanostructure of rat plasma alone.

Abbreviations: AERL, aqueous extract of Rabdosia rubescens leaves; AFM, atomic force microscopy; TEM, transmission electron microscopy.