Table 4.

Correlations between clinical/MRI multiple sclerosis disease variables and work productivity

Variables	Patient characteristics (years)		Physical disability	Work Productivity and Activity Impairment-General Health (%)				Brain volume measures
	Age	Disease duration	EDSS	Activity impairment	Overall work impairment	Absenteeism	Presenteeism	BPV	T1 lesion volume	T2 lesion volume	T1/T2 lesion volume ratio
BPV	−0.370*	−0.199*	−0.219*	−0.150	−0.112	−0.018	−0.132	–	−0.337*	−0.381*	−0.198*
T1 hypointense lesion volume	−0.008	0.147	0.326*	0.157	0.116	0.021	0.138	−0.337*	–	0.869*	0.366*
T2 hyperintense lesion volume	−0.016	0.226*	0.186	0.116	0.062	−0.028	0.090	−0.381*	0.869*	–	0.098
T1/T2 lesion volume ratio	0.173	0.045	0.331*	0.055	0.121	0.147	0.122	−0.198*	0.366*	0.098	–
Baseline EDSS	0.273*	0.286*	–	0.424*	0.195	−0.062	0.211	−0.219*	0.326*	0.186	0.331*
Age at MRI	–	0.374*	0.273*	0.153	−0.015	−0.162	0.123	−0.370*	−0.008	−0.016	0.173
Disease duration	0.374*	–	0.286*	0.197	0.118	−0.039	0.170	−0.199*	0.147	0.226*	0.045

All correlations are Pearson, except for those involving EDSS which are Spearman; Asterisks indicate p value <0.05

BPV brain parenchymal volume, EDSS expanded disability status scale score