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Pharmacokinetics parameters.
| Phase | Tmax(h) | Cmax(ng/ml) | t1∕2(h) | CL/F(L/h) | V/F (L) | AUC0–24h(h·ng/ml) | AUCinf(h·ng/ml) | RA |
|---|---|---|---|---|---|---|---|---|
| Single-dose | 1.5 (0.75–2) | 688.53 ± 140.70% | 5.08 ± 53.11% | 2090.38 ± 85.17% | 15924.60 ± 116.84% | 932.91 ± 81.29% | 956.77 ± 80.28% | |
| Repeated-dose | 1 (0.75–2) | 767.77 ± 224.25% | 5.24 ± 24.31% | 1723.03 ± 83.54% | 19029.00 ± 123.72% | 1078.11 ± 129.72% | 1160.75 ± 121.64% | 1.11 |
Tmax is characterized with median and range, other parameters with geometric mean ± CV%.
