Table 2.
Descriptive data for SV40 expression in DLBCL.
| Variables | Positive SV40 (n = 3) No (%) |
Negative SV40 (n = 82) No (%) |
|---|---|---|
| Age | ||
| ± SD | 31.0 ± 19.5 | 55.2 ± 15.4 |
| Median | 30.0 | 56.0 |
| Range | 12–51 | 2–87 |
| <60 | 1 (2) | 48 (98) |
| ≥60 | 2 (6) | 34 (94) |
| Gender | ||
| Male | 1 (2) | 41 (98) |
| Female | 2 (5) | 41 (95) |
| Primary site of involvement | ||
| Nodal | 2 (4) | 54 (96) |
| Extranodal | 1 (3) | 28 (97) |
| Number of involved extranodal sites | ||
| 0 | 1 (2) | 46 (98) |
| 1-2 | 0 (0) | 32 (100) |
| >2 | 2 (33) | 4 (67) |
| Status | ||
| Generalized | 2 (12) | 14 (88) |
| Localized | 1 (2) | 39 (98) |
| Size (cm) | ||
| ≤10 | 2 (3) | 72 (97) |
| >10 | 1 (9) | 10 (91) |
| Stage grouping | ||
| Early | 0 (0) | 48 (100) |
| Advanced | 3 (8) | 34 (92) |
| PS | ||
| <2 | 0 (0) | 14 (100) |
| ≥2 | 3 (4.2) | 68 (95.8) |
| B symptoms | ||
| Present | 2 (4) | 49 (96) |
| Absent | 1 (3) | 33 (97) |
| LDH | ||
| Normal | 0 (0) | 11 (100) |
| Elevated | 3 (4) | 71 (96) |
| Prognostic group of R-IPI | ||
| Good | 0 (0) | 29 (100) |
| Poor | 3 (5) | 53 (95) |
| Risk groups of AAIPI ≥60 | ||
| Low | 0 (0) | 0 (0) |
| Intermediate | 0 (0) | 0 (0) |
| High | 2 (14) | 0 (0) |
| Risk groups of AAIPI <60 | ||
| Low | 0 (0) | 0 (0) |
| Intermediate | 0 (0) | 0 (0) |
| High | 1 (100) | 0 (0) |
| Type of DLBCL | ||
| Germinal | 2 (4) | 47 (96) |
| Nongerminal | 1 (2.8) | 35 (97.2) |
| Necrosis | ||
| Present | 0 (0) | 14 (100) |
| Absent | 3 (14) | 68 (96) |
| ± SD | — | 34.29 ± 22.43 |
| Range | — | 10.0–80.0 |
| Mitosis | ||
| ± SD | 21.3 ± 1.5 | 22.5 ± 9.7 |
| Range | 20–23 | 6–46 |
| Media | 21.0 | 21.5 |
| Ki-67 LI | ||
| <50 | 3 (4) | 74 (96) |
| ≥50 | 0 (0) | 8 (100) |
| Apoptosis | ||
| ± SD | 12.7 ± 3.1 | 13.5 ± 6.5 |
| Range | 10–16 | 3–31 |
| Median | 12 | 13 |
R-IPI: revised international prognostic index; AAIPI: age adjusted international prognostic index.
PS: performance status; LDH: lactate dehydrogenase; Ki-67 LI: Ki-67 labeling index.
DLBCL: diffuse large B-cell lymphoma.