Table 3.
Univariate and multivariate analyses of risk factors associated with death during TB treatment.
| Characteristics | Death | Univariate | Multivariate | |||||
|---|---|---|---|---|---|---|---|---|
| Yes n = 146 |
(%) | No n = 1111 |
(%) | OR (95% CI) | p | OR (95% CI) | p | |
| Age | ||||||||
| <40 years | 48 | (34.0) | 625 | (57.0) | 1.0 | |||
| >40 years | 93 | (66.0) | 472 | (43.0) | 2.57 (1.75–3.77) | <0.001 | 2.61 (1.76–3.85) | <0.001 |
| Gender | ||||||||
| Female | 38 | (26.0) | 351 | (31.6) | 1.0 | |||
| Male | 108 | (74.0) | 760 | (68.4) | 1.31 (0.87–1.98) | ns | ||
| HIV coinfection | ||||||||
| No | 106 | (72.6) | 1034 | (93.1) | 1.0 | |||
| Yes | 40 | (27.4) | 77 | (6.9) | 5.07 (3.22–7.97) | <0.001 | 6.01 (3.78–9.56) | <0.001 |
| Alcoholic | ||||||||
| No | 127 | (87.0) | 995 | (89.6) | 1.0 | |||
| Yes | 19 | (13.0) | 116 | (10.4) | 1.28 (0.74–2.21) | ns | ||
| Literacy | ||||||||
| Yes | 89 | (61.0) | 854 | (76.9) | 1.0 | |||
| No | 57 | (39.0) | 257 | (23.1) | 2.13 (1.46–3.10) | <0.001 | 1.88 (1.27–2.78) | 0.002 |
| Treatment in the same city of residence | ||||||||
| Yes | 119 | (81.5) | 961 | (86.5) | 1.0 | |||
| No | 27 | (18.5) | 150 | (13.5) | 1.45 (0.90–2.33) | ns | ||
| Area | ||||||||
| Countryside | 12 | (8.2) | 138 | (12.4) | 1.0 | |||
| Urban area | 134 | (91.8) | 973 | (87.6) | 1.58 (0.83–3.09) | ns | ||
| Institutionalized | ||||||||
| No | 145 | (99.3) | 1059 | (95.3) | 1.0 | |||
| Yes | 1 | (0.7) | 52 | (4.7) | 0.14 (0.00–0.83) | 0.024 | — | ns |
| Extrapulmonary TB | ||||||||
| No | 116 | (79.5) | 904 | (81.4) | 1.0 | |||
| Yes | 30 | (20.5) | 207 | (18.6) | 1.13 (0.72–1.77) | ns | ||
| Severe extrapulmonary TB∗ | ||||||||
| No | 130 | (89.0) | 1056 | (95.0) | 1.0 | |||
| Yes | 16 | (11.0) | 55 | (5.0) | 2.36 (1.26–4.39) | 0.003 | 2.33 (1.24–4.38) | 0.009 |
| Diabetes | ||||||||
| No | 136 | (93.2) | 1042 | (93.8) | 1.0 | |||
| Yes | 10 | (6.8) | 69 | (6.2) | 1.10 (0.52–2.29) | ns | ||
| Cigarette smoking | ||||||||
| No | 139 | (95.2) | 1026 | (92.3) | 1.0 | |||
| Yes | 7 | (4.8) | 85 | (7.7) | 0.61 (0.23–1.34) | ns | ||
| Comorbidity | ||||||||
| No | 121 | (82.9) | 1007 | (90.6) | 1.0 | |||
| Yes | 25 | (17.1) | 104 | (9.4) | 2.00 (1.21–3.29) | 0.004 | — | ns |
| Treatment after relapse | ||||||||
| No | 131 | (89.7) | 1057 | (95.1) | 1.0 | |||
| Yes | 15 | (10.3) | 54 | (4.9) | 2.24 (1.17–4.22) | 0.007 | 1.95 (1.01–3.75) | 0.046 |
| Treatment after abandonment | ||||||||
| No | 132 | (90.4) | 1019 | (91.7) | 1.0 | |||
| Yes | 14 | (9.6) | 92 | (8.3) | 1.17 (0.62–2.19) | ns | ||
∗Meningitis, miliary, pericarditis, peritonitis, bilateral or extensive pleural effusion, spinal, genitourinary, and intestinal types.
ns: not significant.