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. 2015 Nov 10;5:16469. doi: 10.1038/srep16469

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Copyright © 2015, Macmillan Publishers Limited

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Synovial membrane (upper panel) and infrapatellar fat pad (lower panel) were isolated from patients undergoing primary TKA (left panel), patients undergoing non-arthrofibrotic revision TKA (middle panel) and patients undergoing arthrofibrotic revision TKA (right panel). Both tissues from primary TKA patients appeared to be homogenous, fatty, non-fibrotic tissue. In contrast, tissue from revision TKA patients appeared to be dense, pigmented, fibrotic tissue regardless of clinical diagnosis. Images acquired by Dr Lee Borthwick.