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. 2015 Nov 10;5:16469. doi: 10.1038/srep16469

Figure 7. Increased expression of fibronectin positive cells in tissue from revision TKA.

Figure 7

(a) Representative images of fibronectin stained synovial membrane (upper panel) and infrapatellar fat pad (lower panel) from patients undergoing primary TKA (left panel), patients undergoing non-arthrofibrotic revision TKA (middle panel) and patients undergoing arthrofibrotic revision TKA (right panel). Fibronectin staining is increase in revision TKA tissue compared to primary TKA tissue. Images acquired on a Nikon inverted microscope at 20× magnification. (b) Fibronectin positive staining was quantified using image analysis software. There was a significant increase in fibronectin positive staining of synovial membrane (i) and infrapatellar fat pad (ii) from revision patients compared to primary TKA regardless of clinical diagnosis. There was no significant difference in fibronectin positive staining of either tissue between patients undergoing non-arthrofibrotic revision TKA and patients undergoing arthrofibrotic revision TKA. Synovial membrane and Infrapatellar fat pad; primary TKA n = 9, non-arthrofibrotic revision TKA n = 10, arthrofibrotic revision TKA n = 10. ****p < 0.0001.

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