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. 2015 Nov 10;5:16414. doi: 10.1038/srep16414

Figure 5.

Figure 5

Activity of 39 current and candidate antimalarial drugs on mature P. falciparum 3D7A gametocytes and their rounding-up process. Scatterplot of activities of all compounds Compounds were tested at 10 μM concentration. Red and green lines represent 50% activity thresholds for functional viability and total gametocytes readout, respectively. Five compounds showing a higher inhibition on gametes than on total gametocytes are shown as blue squares (thiostrepton, cycloheximide, artemisone, atovaquone and primaquine).