Table 3. Effect of GT on Cr and BUN (mg/dL) in 14 rats (7 rats/group).
| Cr | BUN | |||
|---|---|---|---|---|
| Treatments | Water | GT | Water | GT |
| Day 0 | 0.30 ± 0.0 | 0.30 ± 0.0 | 21.1 ± 0.9 | 20.9 ± 1.2 |
| Day 4 | 0.59 ± 0.0 | 0.57 ± 0.0 | 67.0 ± 6.3 | 53.1 ± 2.2 |
| Day 8 | 0.49 ± 0.0 | 0.79 ± 0.1* | 40.9 ± 3.3 | 55.1 ± 5.7** |
*P < 0.05 compared to water group.
Day 0: before adenine treatment.
Day 4: before GT dosing.
Day 8: after 7th dose of GT and water.
Data expressed as mean ± S.E.