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. 2015 Nov 10;5:16222. doi: 10.1038/srep16222

Table 2. Effect of P2X7 knockdown on the synergy between Ivermectin and ATP.

CI values <0.8 Synerg 0.8-1.2 Addit >1.2 Antag
4T1.2 shRNA (P2×7)
  I 6 I 8 I 10
ATP 1 1.49 1.39 1.35
ATP 2 1.18 1.03 1.11
ATP 3 0.96 0.91 0.86
4T1.2 shRNA (NT)
ATP 1 1.18 1.01 1.24
ATP 2 1.17 1.01 1.10
ATP 3 0.67 0.64 0.63