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. 2015 Nov 9;211(3):683–701. doi: 10.1083/jcb.201501106

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© 2015 Guetta-Terrier et al.

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Figure 1. — Cells migrate faster and harbor higher persistence on suspended nanofibers mimicking a fibrillar environment. (A) Drawing of cells plated on fibronectin for continuous surface, microprinted lines or suspended fibers. (B) Snapshots of 3T3 cell movement over 6 h (1 frame/h) on line (left) or fiber (right). Bar, 10 µm. (C–E) Typical trajectories of 13 3T3 fibroblasts on continuous surface (C), lines (D), and fibers (E) for 6 h. Each colored trajectory is one single cell. (F) Quantification of linear speed and (G) persistence: continuous surface (red), line (green), and fiber (blue). Error bar, SEM, from four independent experiments; *, P < 0.001 (Student's t test); number of cells (NB), 203 (2D), 211 (line), and 222 (fiber).