Figure 4.
Fin-like protrusive waves are correlated with cell polarity. (A) Kymograph of 3T3 on fiber. Three distinct states were observed: a spreading-immobile state (I), a migrating state (II), and a faster migrating state (III). (B and C) Linear speed as a function of cell length (normal and log-log plot). Number of cells (NB), 35. (D) Velocity of protrusion as a function of cell length. NB, 22. (E) Frequency of protrusion as a function of cell length. NB, 22. (F) Kymograph of 3T3 switching behavior on fiber. (G) Kymograph of 3T3 cell during postmitotic spreading switching behavior as in F. White arrows in F and G show new fin generation at the trailing edge.