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. 2015 Oct;14(5):583–591. doi: 10.7785/tcrtexpress.2013.600280

Table III.

Treatment and dose-volume parameters, monitor units, and beam-on times of the four TomoDirect plans for patients with locally advanced lung cancer.

Mean ± standard deviation
2.5-cm Dynamic 2.5-cm Fixed p* 5.0-cm Dynamic 5.0-cm Fixed p** p***
Patient number 25
Total PTV (ml) 338.7 ± 179.0
Pitch 0.251 0.500
Modulation factor 2.0
Conformity index 12.5 ± 13.0 13.3 ± 13.8 0.002 11.3 ± 10.4 13.3 ± 12.3 0.77 0.08
Uniformity index 1.09 ± 0.04 1.10 ± 0.05 0.003|| 1.10 ± 0.05 1.11 ± 0.05 0.0001|| 0.08§
Monitor unit 3509 ± 601 3417 ± 596 <0.0001 1912 ± 294 1806 ± 292 <0.0001 <0.0001
Beam-on time (sec) 287.9 ± 42.1 281.3 ± 41.9 <0.0001 175.7 ± 20.6 168.3 ± 20.4 <0.0001 <0.0001
Body
 V5 Gy (ml) 4848.5 ± 1337.5 5197.4 ± 1402.4 <0.0001|| 5220.2 ± 1442.8 6153.9 ± 1599.0 <0.0001|| <0.0001§
 V10 Gy (ml) 4287.4 ± 1175.3 4602.2 ± 1241.8 <0.0001|| 4628.7 ± 1282.5 5418.1 ± 1433.5 <0.0001|| <0.0001§
 V20 Gy (ml) 3737.7 ± 1046.8 3929.5 ± 1089.1 <0.0001|| 3999.5 ± 1134.9 4500.7 ± 1247.8 <0.0001|| <0.0001§
 V30 Gy (ml) 3282.8 ± 933.6 3405.4 ± 972.5 <0.0001|| 3488.7 ± 1000.2 3762.4 ± 1074.1 <0.0001|| <0.0001§
Spinal cord maximum (Gy) 43.3 ± 2.2 43.5 ± 2.4 0.11|| 43.1 ± 2.2 43.1 ± 2.0 0.94|| 0.09§
Esophagus maximum (Gy) 59.4 ± 2.2 59.0 ± 2.4 0.05|| 58.2 ± 2.7 58.3 ± 2.8 0.27|| <0.0001§
Heart V40 Gy (%) 7.9 ± 7.7 8.3 ± 7.7 0.01|| 10.4 ± 9.6 11.2 ± 9.6 0.02|| <0.0001§

Abbreviation: PTV: Planning target volume.

*p-value between 2.5-cm dynamic- and 2.5-cm fixed-jaw plans.

**p-value between 5.0-cm dynamic- and 5.0-cm fixed-jaw plans.

***p-value among the four plans.

Calculated by Friedman analysis of variance.

Calculated by Wilcoxon signed-rank test.

§Calculated by parametric analysis of variance for depended samples.

||Calculated by paired t-test.