Table IV.
Dose-volume parameters of the four TomoDirect plans for patients with locally advanced lung cancer.
| Mean ± standard deviation | |||||||
|---|---|---|---|---|---|---|---|
| 2.5-cm Dynamic | 2.5-cm Fixed | p* | 5.0-cm Dynamic | 5.0-cm Fixed | p** | p*** | |
| Total lung | |||||||
| V5 Gy (%) | 37.3 ± 11.0 | 38.7 ± 11.4 | <0.0001|| | 40.4 ± 11.7 | 44.0 ± 12.4 | <0.0001|| | <0.0001§ |
| V10 Gy (%) | 31.1 ± 9.6 | 32.3 ± 10.0 | <0.0001|| | 34.4 ± 10.6 | 37.1 ± 11.2 | <0.0001|| | <0.0001§ |
| V20 Gy (%) | 25.0 ± 7.9 | 25.5 ± 8.4 | 0.007|| | 27.5 ± 8.9 | 29.2 ± 9.5 | <0.0001|| | <0.0001§ |
| V30 Gy (%) | 20.7 ± 6.6 | 21.0 ± 7.0 | 0.09|| | 22.7 ± 7.4 | 23.3 ± 7.7 | <0.0001|| | <0.0001§ |
| V40 Gy (%) | 17.2 ± 6.2 | 16.8 ± 5.8 | 0.40|| | 18.1 ± 6.1 | 18.1 ± 6.2 | 0.82|| | <0.0001§ |
| V50 Gy (%) | 12.7 ± 5.3 | 12.3 ± 4.2 | 0.43|| | 12.8 ± 4.6 | 12.5 ± 4.6 | 0.0006|| | 0.53§ |
| MLD (Gy) | 13.7 ± 4.0 | 14.1 ± 4.1 | <0.0001|| | 14.8 ± 4.4 | 15.6 ± 4.5 | <0.0001|| | <0.0001§ |
| Ispilateral lung | |||||||
| V5 Gy (%) | 53.5 ± 19.4 | 55.5 ± 20.0 | <0.0001|| | 56.8 ± 19.7 | 62.7 ± 20.7 | <0.0001|| | <0.0001§ |
| V10 Gy (%) | 46.3 ± 17.4 | 48.2 ± 18.1 | <0.0001|| | 50.0 ± 18.1 | 55.2 ± 19.6 | <0.0001|| | <0.0001§ |
| V20 Gy (%) | 38.4 ± 14.7 | 39.6 ± 15.1 | <0.0001|| | 42.4 ± 16.0 | 45.3 ± 17.1 | <0.0001|| | <0.0001§ |
| V30 Gy (%) | 32.6 ± 12.9 | 33.3 ± 13.1 | 0.0002|| | 35.9 ± 14.1 | 37.0 ± 14.4 | <0.0001|| | <0.0001§ |
| V40 Gy (%) | 26.9 ± 11.2 | 27.3 ± 11.3 | 0.03|| | 29.3 ± 12.2 | 28.8 ± 2.2 | 0.22|| | 0.009§ |
| V50 Gy (%) | 20.6 ± 9.1 | 21.0 ± 9.4 | 0.13|| | 21.7 ± 9.8 | 21.1 ± 9.3 | 0.003|| | 0.003§ |
| Contralateral lung | |||||||
| V5 Gy (%) | 23.4 ± 9.9 | 24.1 ± 10.3 | <0.0001|| | 27.0 ± 11.9 | 28.7 ± 13.0 | 0.0005|| | <0.0001§ |
| V10 Gy (%) | 18.1 ± 8.1 | 18.8 ± 8.4 | 0.0008|| | 21.1 ± 9.9 | 22.2 ± 10.9 | 0.002|| | <0.0001§ |
| V20 Gy (%) | 13.4 ± 6.8 | 13.6 ± 7.0 | 0.006|| | 15.3 ± 8.2 | 15.8 ± 8.7 | 0.007|| | <0.0001§ |
| V30 Gy (%) | 10.6 ± 6.0 | 10.6 ± 6.1 | 0.49|| | 11.7 ± 7.1 | 12.0 ± 7.3 | 0.02|| | 0.001§ |
| V40 Gy (%) | 8.2 ± 5.2 | 8.2 ± 5.2 | 0.41|| | 8.9 ± 5.9 | 9.0 ± 6.0 | 0.12|| | 0.03§ |
| V50 Gy (%) | 5.2 ± 3.9 | 5.2 ± 3.9 | 0.65|| | 5.6 ± 4.5 | 5.6 ± 4.4 | 0.66|| | 0.29§ |
*p-value between 2.5-cm dynamic- and 2.5-cm fixed-jaw plans.
**p-value between 5.0-cm dynamic- and 5.0-cm fixed-jaw plans.
***p-value among the four plans.
§Calculated by parametric analysis of variance for depended samples.
||Calculated by paired t-test.