Figure 1. Schematic drawing of a Drosophila early egg chamber and a human primary follicle at equivalent stages of oogenesis.

(A) A Drosophila early egg chamber. The inset illustrates that NUP107 plays a critical cell-autonomous role in regulating the Drosophila follicle cell development. (B) A human primary follicle. NUP107 might play a role in follicle-cell communication with the oocyte as well as a cell-autonomous role in oocyte development. Cell types are indicated in the figure.