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. 2015 Oct 2;112(40):672–679. doi: 10.3238/arztebl.2015.0672

Tablle 2. Findings of per-protocol and intention-to-treat analyses for primary outcomes “confidence in decision” and “satisfaction with decision” at time t1.

Control group Intervention group Significance Effect size
Breast cancer Colon cancer Total Breast cancer Colon cancer Total Group Cancer type Interaction Group
M (SD); n M (SD); n M (SD); n M (SD); n M (SD); n M (SD); n p p p d*3 (95% CI)
Confidence in decision*1
Per-protocol
Intention-to-treat*2
83.2 (20.8); 51
82.5 (18.5); 142
77.2 (22.7); 28
78.0 (18.3); 79
81.0 (21.5); 79
81.0 (18.4); 224
83.7 (12.0); 18
84.2 (18.1); 103
78.7 (17.5); 24
78.3 (16.3); 85
80.9 (15.4); 42
81.5 (17.4); 190
0.925
0.740
0.204
0.123
0.891
0.955
0.03
(–0.35 to 0.40)
Satisfaction with decision*1
Per-protocol
Intention-to-treat*2
83.6 (17.4); 52
83.2 (15.3); 145
80.6 (20.9); 27
79.8 (16.8); 79
82.6 (18.6); 79
82.0 (15.7); 223
90.0 (11.0); 17
86.4 (13.9); 114
85.9 (12.6); 23
84.4 (13.4); 82
87.7 (12.0); 40
85.6 (14.1); 201
0.182
0.310
0.460
0.243
0.874
0.762
0.24
(–0.14 to 0.62)

Full findings reported in eMethods.

M, mean; SD, standard deviation; n, sample size; CI, confidence interval; d , Cohen’s d

*1Scores range from 0 to 100. 0 is low, 100 high for satisfaction with decision/confidence in decision.

*2Intention-to-treat analysis assuming the most likely scenario: missing values for the control group were estimated on the basis of available data from the control group; missing values for physicians in the intervention group who had undergone training were estimated on the basis of available data from the intervention group; missing values for physicians in the intervention group who had not undergone training were estimated on the basis of data from the control group.

*3Cohen’s d was estimated on the basis of the means and standard deviations of the intention-to-treat analysis and sample size of the per-protocol analysis