Tablle 2. Findings of per-protocol and intention-to-treat analyses for primary outcomes “confidence in decision” and “satisfaction with decision” at time t1.
Control group | Intervention group | Significance | Effect size | |||||||
---|---|---|---|---|---|---|---|---|---|---|
Breast cancer | Colon cancer | Total | Breast cancer | Colon cancer | Total | Group | Cancer type | Interaction | Group | |
M (SD); n | M (SD); n | M (SD); n | M (SD); n | M (SD); n | M (SD); n | p | p | p | d*3 (95% CI) | |
Confidence in decision*1 Per-protocol Intention-to-treat*2 |
83.2 (20.8); 51 82.5 (18.5); 142 |
77.2 (22.7); 28 78.0 (18.3); 79 |
81.0 (21.5); 79 81.0 (18.4); 224 |
83.7 (12.0); 18 84.2 (18.1); 103 |
78.7 (17.5); 24 78.3 (16.3); 85 |
80.9 (15.4); 42 81.5 (17.4); 190 |
0.925 0.740 |
0.204 0.123 |
0.891 0.955 |
0.03 (–0.35 to 0.40) |
Satisfaction with decision*1 Per-protocol Intention-to-treat*2 |
83.6 (17.4); 52 83.2 (15.3); 145 |
80.6 (20.9); 27 79.8 (16.8); 79 |
82.6 (18.6); 79 82.0 (15.7); 223 |
90.0 (11.0); 17 86.4 (13.9); 114 |
85.9 (12.6); 23 84.4 (13.4); 82 |
87.7 (12.0); 40 85.6 (14.1); 201 |
0.182 0.310 |
0.460 0.243 |
0.874 0.762 |
0.24 (–0.14 to 0.62) |
Full findings reported in eMethods.
M, mean; SD, standard deviation; n, sample size; CI, confidence interval; d , Cohen’s d
*1Scores range from 0 to 100. 0 is low, 100 high for satisfaction with decision/confidence in decision.
*2Intention-to-treat analysis assuming the most likely scenario: missing values for the control group were estimated on the basis of available data from the control group; missing values for physicians in the intervention group who had undergone training were estimated on the basis of available data from the intervention group; missing values for physicians in the intervention group who had not undergone training were estimated on the basis of data from the control group.
*3Cohen’s d was estimated on the basis of the means and standard deviations of the intention-to-treat analysis and sample size of the per-protocol analysis