Table 7.
Comparison of CHAMACOS autosomal sex-associated CpG sites (n = 3031) with other published studies
| Study | Study population | Tissue | Platform | Number of autosomal hits | Number of CHAMACOS hits replicated (%) | Percent of concordance in direction of methylation differences among replicated sites |
|---|---|---|---|---|---|---|
| McCarthy et al. 2014 [18] | Meta analysis of 76 studies (n = 6,795) | Multiple types | Illumina 27 K | 184 | 54 (29.4 %) | 100 % |
| Xu et al. 2014 [39] | 46 Caucasian adults | postmortem prefrontal cortex | Illumina 450 K | 614 | 260 (42.4 %) | 98.50 % |
| Hall et al. 2014 [40] | 87 Caucasian adults | pancreas | Illumina 450 K | 470 | 176 (37.5 %) | 100 % |