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. Author manuscript; available in PMC: 2015 Nov 10.
Published in final edited form as: Hum Mutat. 2012 Jun 7;33(8):1188–1191. doi: 10.1002/humu.22114

Figure 1. Schematic representation of SCN5A protein showing known disease-causing residues and those predicted to be disease-causing by paralogous annotation.

Figure 1

Previously annotated disease-causing residues are shown in black. Predicted disease-causing residues are shown in red. Coincidences of known and predicted variants are denoted by a blue dot. A schematic of the protein is shown below the variants with color-coding of protein domains. All known variants and novel paralogue mappings for this and for the other seven LQT genes are shown in Supp. Figure S1.