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. Author manuscript; available in PMC: 2015 Nov 10.
Published in final edited form as: Semin Cancer Biol. 2014 Apr 23;28:3–13. doi: 10.1016/j.semcancer.2014.04.009

Figure 1. Exosomes contain specific repertoires of proteins, RNAs and lipids.

Figure 1

(A) The molecular composition of exosomes is not a reflection of the cell. Exosomes are enriched in specific proteins, lipids and RNAs, whereas others are absent, indicating the existence of specialized mechanisms that control the sorting of molecules into exosomes. (B) The stress-induced changes in exosomal RNA and protein composition can influence the response of distant cells to stress by providing protective signals (surveillance, drug resistance, etc.).