TABLE 1.
Baseline Demographic and Smoking Characteristics
| Placebo |
Naltrexone |
|||
|---|---|---|---|---|
| Variable | Men (n = 71) | Women (n = 83) | Men (n = 76) | Women (n = 85) |
| Age, mean (SD), y | 40.6* (11.0) | 44.3 (10.0) | 38.2* (11.3) | 44.1 (12.0) |
| Education (years completed), mean (SD) | 15.1 (1.7) | 15.0 (2.7) | 15.4 (2.6) | 14.8 (2.8) |
| Hollingshead index, mean (SD) | 46.4 (13.5) | 46.6 (12.8) | 46.3 (14.8) | 45.6 (13.8) |
| Body mass index, mean (SD), kg/m2 | 26.7 (4.2) | 27.1 (4.6) | 26.9 (4.4) | 27.3 (4.6) |
| Drinks per week in current drinkers,* mean (SD) | 8.6 (9.3) | 5.1 (9.1) | 7.7 (7.8) | 3.8 (3.7) |
| Cigarettes per day, mean (SD) | 21.7† (7.6) | 19.1 (5.5) | 19.0 (5.2) | 19.2 (5.5) |
| Age of smoking initiation, mean (SD) | 15.0 (3.4) | 14.8 (3.6) | 15.2 (3.5) | 15.2 (4.6) |
| Carbon monoxide level, mean (SD), ppm | 24.8 (15.2) | 24.0 (10.9) | 23.0 (10.5) | 21.3 (11.1) |
| Nicotine dependence (FTND), mean (SD) | 5.5 (1.7) | 5.3 (1.8) | 4.8 (1.7) | 5.3 (1.8) |
| Smoking urge (BQSU), mean (SD) | 28.5 (11.8) | 28.7 (11.4) | 29.9 (9.9) | 30.9 (11.6) |
| No. past quit attempts (>12 h), mean (SD) | 4.4 (5.1) | 3.8 (6.4) | 5.5 (13.9) | 3.8 (3.7) |
| Beck Depression Inventory, mean (SD) | 4.7 (4.8) | 4.1 (4.5) | 3.6 (4.0) | 3.4 (3.4) |
| Race, n (%) | ||||
| Caucasian | 46 (64.8) | 47 (56.6) | 44 (57.9) | 44 (51.8) |
| African American | 22 (31) | 30 (36.2) | 20 (26.3) | 38 (44.7) |
| Asian | 1 (1.4) | 1 (1.2) | 5 (6.6) | 1 (1.2) |
| More than 1 race/other | 2 (2.8) | 5 (6) | 7 (9.2) | 2 (2.3) |
| Ethnicity (non-Hispanic), n (%) | 67 (94.4) | 80 (96.4) | 73 (96.1) | 83 (97.6) |
| Married or living with partner, n (%) | 25 (35) | 25 (33) | 28 (34) | 24 (28) |
| Sexual preference for opposite sex, n (%) | 60 (85.7) | 76 (91.6) | 61 (81.3) | 78 (91.8) |
| Current alcohol drinker, n (%) | 60 (87) | 71 (90) | 69 (93) | 72 (86) |
Current alcohol drinker defined as consuming at least one drink in past six months.
*
Drinks per week were analyzed taking into account the participants’ body water estimates.
†
Sex difference, P < 0.05.
BQSU indicates Brief Questionnaire of Smoking Urges; FTND, Fagerström Test of Nicotine Dependence.