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. Author manuscript; available in PMC: 2016 Nov 5.
Published in final edited form as: Cell. 2015 Nov 5;163(4):960–974. doi: 10.1016/j.cell.2015.10.034

Figure 3. ERβ-Specific Antagonist Regresses Ectopic Lesion Growth.

Figure 3

(A) Ectopic lesions isolated from C57BL/6J mice with endometriosis subcutaneously treated with vehicle or PHTPP.

(B and C) IHC and quantitative analyses of hrGFP levels in ectopic lesions (B) and eutopic endometria (C) of ERBAI mice with endometriosis subcutaneously treated with vehicle or PHTPP.

(D and E) IHC and quantitative analyses of the expression patterns of Ki-67 (D) and cleaved CSP8 (E) in ectopic lesions of C57BL/6J mice with endometriosis subcutaneously treated with vehicle or PHTPP.

(F and G) IHC and quantitative analyses of the levels of Ki-67 (F) and cleaved CSP8 (G) in the eutopic endometria of C57BL/6J mice with endometriosis subcutaneously treated with vehicle or PHTPP. PLC, percentage of labeled cells. CSP8, caspase 8. See also Figures S2.