. Author manuscript; available in PMC: 2016 Nov 5.

Published in final edited form as: Cell. 2015 Nov 5;163(4):960–974. doi: 10.1016/j.cell.2015.10.034

Table 1.

Proliferation and apoptosis in ectopic lesions and eutopic endometrium of PHTPP-treated, ERβ^−/− and ERβ:OE mice with endometriosis.

Cellular Process	Type of endometrium	Compartment	PHTPP	ERB^−/−	ERB:OE
Proliferative Activity	Ectopic lesions	Epithelium	−	−	+
	Ectopic lesions	Stromal	0	0	+
	Eutopic Endometrium	Epithelium	−	0	+
	Eutopic Endometrium	Stromal	−	0	+
Apoptosis Signaling	Ectopic lesions	Epithelium	+	+	−
	Ectopic lesions	Stromal	+	0	−
	Eutopic Endometrium	Epithelium	+	+	0
	Eutopic Endometrium	Stromal	0	+	0
Ectopic lesion Volume			−	−	+

(+: Increased, 0: No change, -:Decreased compared to vehicle treatment, wild type, or control mice)