Figure 2.

Forest plot of the SMD of LINE-1 methylation levels between colorectal cancer and control groups.

Note: The subgroup analysis was based on ethnicity. Weights are from random effects analysis. *There is only one study in the Asian subgroup, so the I² of the subgroup is blank in the output graph.

Abbreviations: FCCX, familial colorectal cancer type X; MSI, microsatellite instability; MSS, microsatellite stability; LINE-1, long interspersed element-1; SMD, standardized mean difference; CI, confidence interval.