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. 2015 Nov 5;8:3265–3276. doi: 10.2147/OTT.S91941

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© 2015 Tang et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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Forest plot of the SMD of LINE-1 methylation levels between several molecular features in CRC.

Notes: (A) Forest plot of the SMD of LINE-1 methylation levels between KRAS-wild-type tumor and KRAS-mutant tumor. (B) Forest plot of the SMD of LINE-1 methylation levels between PIK3CA-wild-type tumor and PIK3CA-mutant tumor. (C) Forest plot of the SMD of LINE-1 methylation levels between tumors that lost the ability to express p21 and p21 expressing tumors.

Abbreviations: CI, confidence interval; CRC, colorectal cancer; LINE-1, long interspersed element-1; SMD, standardized mean difference.