Figure 1.

Glutamic acid excitotoxicity model; poly-arginine peptide dose response experiments. (A–C) Peptides present in neuronal cultures for 15 minutes before and during 5-minute glutamic acid exposure. Neuronal viability measured 20 to 24 hours after glutamic acid exposure. Concentration of peptide in μmol/L. MTS data were expressed as percentage neuronal viability with no insult control taken as 100% viability (mean±s.d.; n=4; *P<0.05). MTS, 3-(4,5,dimethyliazol-2-yl)-5-(3-carboxymethoxy-phenyl)-2-(4-sulfophenyl)-2H-tetrazolium salt.