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. 2015 May 6;35(7):1076–1084. doi: 10.1038/jcbfm.2015.84

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Copyright © 2015 International Society for Cerebral Blood Flow & Metabolism, Inc.

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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(A) Speckle contrast images at six separate exposures exhibiting increased speckle visibility (e.g., contrast) at lower exposures and highlighting varying flow range sensitivity with exposure selection. (B) Fraction of collected light at each pixel scattered by moving particles (i.e., dynamically scattered light, ρ of Equation 3) and (C) corresponding inverse correlation time map extracted from fitting speckle contrast relationship with exposure duration, K(T), to the visibility expression in Equation 3.