Table 1. Demographic data of the Groningen and North Shore PD cohorts.
HC | PD | P-valuea | |
---|---|---|---|
A. Groningen sample for derivation of PDCPGR | |||
Number of subjects | 17 | 19 | — |
Gender, F/M | 5/12 | 6/13 | 0.89 |
Age, years | 61.1±7.4 (51.5–78)b | 63.7±7.7 (49–76) | 0.3 |
Disease duration, years | NA | 4.4±3.2 (1.5–11.5) | — |
UPDRS (off-state motor) | NA | 18.4±7.4 (9–32) | — |
MMSE | 29.4±0.9 (27–30) | 28.5±1.1 (26–30) | 0.01 |
FAB | 17.5±0.8 (15–18) | 15.7±1.9 (11–18) | 0.001 |
B. North Shore testing sample | |||
Number of subjects | 15 | 86 | — |
Gender, F/M | 7/8 | 27/59 | 0.25 |
Age, years | 56.7±12.3 (37–76.8) | 60.8±8.2 (37–77) | 0.23 |
Disease duration, years | NA | 12.5±5.9 (4–32) | — |
UPDRS (off-state motor) | NA | 31.6±14.4 (10–67) | — |
MMSE | NA | 28.0±1.4 (25–30) | — |
Abbreviations: F, female; FAB, Frontal Assessment Battery; HC, healthy controls; M, male; MMSE, Mini Mental State Examination; PD, Parkinson's disease; PDCPGR, Groningen PD cognition-related pattern; UPDRS, Unified Parkinson's Disease Rating Scale.
χ2 test for gender; two sample t-test for age; Mann–Whitney U-test for MMSE and FAB.
Data are shown as mean±s.d. (range).