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. 2015 Jun 10;35(9):1478–1484. doi: 10.1038/jcbfm.2015.112

Table 2. Brain regions with significant contributions to the Parkinson's disease-related cognitive pattern derived from the Groningen data (PDCPGR).

Brain regiona Coordinatesb Zmaxc
  x y z  
Network-related decreases (negative voxel weights)
 Thalamus (mediodorsal nucleus) 0 −16 2 4.35
 Caudate nucleus −10 8 6 3.32
 Supplementary motor area (rostral, BA 6) 2 14 50 4.11
 Superior parietal association cortex, BA 5 0 −38 54 3.77
 Inferior parietal cortex, BA 7, 40 46 −54 60 3.54
 Posterior cingulate cortex, BA 29 0 −52 6 3.64
            BA 23 −2 −24 28 3.19
         
Network-related increases (positive voxel weights)
 Cerebellum, lobule VI, Crus I 28 −52 −38 2.49
 Anterior cingulate, BA 32, right 20 42 −2 2.59
         BA 32, left −18 38 16 2.55

Abbreviation: BA, Brodmann area.

a

All brain regions are significant at Z>2.44 (P<0.01) and stable on bootstrap resampling (P<0.01).

b

Montreal Neurological Institute standard space.

c

Maximum voxel weights in Z-scores.