Table 1. Hemodynamics and arterial blood gases.
| Baseline | iHS | HS 6 hours | LEH 6 hours | SAL 6 hours | |
|---|---|---|---|---|---|
| Hematocrit | 40.57±1.02 | ND | 25.33±1.14* | 22.4±2.28* | 23.25±0.52* |
| Heart rate (beats/min) | 317±1.8 | 192±2.62* | 236±10.5*¥ | 257±26.9*¥ | 225±16.8*¥ |
| MAP (mm Hg) | 108.6±0.58 | 48.6±0.77* | 60.7±4.03*¥ | 78.9±3.05*¥$ | 77.3±3.18*¥$ |
| pH | 7.51±0.01 | ND | 7.49±0.01 | 7.26±0.08*$ | 7.48±0.01ϕ |
| HCO3 (mmol/L) | 29.67±1.65 | ND | 27.27±1.20 | 15.92±1.15*$ | 27.45±0.89 |
| Anion gap | 10.68±1.40 | ND | 14.95±3.19 | 18.73±1.98 | 9.15±0.57 |
| Total CO2 (mmol/L) | 29.17±0.58 | ND | 28.45±1.28 | 17.16±1.14*$ | 28.65±0.89ϕ |
| Base excess (mmol/L) | 5.53±0.29 | ND | 4.23±0.98 | -10.04±2.38*$ | 4.25±0.94ϕ |
| pO2 (mm Hg) | 85.67±1.71 | ND | 106.00±6.65 | 89.40±19.74 | 101.75±1.65 |
| Total Hb (g/dL) | 15.38±0.15 | ND | 6.45±0.29* | 8.64±0.41*$ | 7.25±0.22*ϕ |
| Na+ (mmol/L) | 140.67±0.76 | ND | 139.17±1.08 | 140.60±1.94 | 139.50±0.65 |
| K+ (mmol/L) | 4.20±0.07 | ND | 4.08±0.14 | 4.57±0.72 | 4.03±0.19 |
| Cl− (mmol/L) | 106.17±0.91 | ND | 104.33±1.17 | 109.00±0.95$ | 106.50±0.29 |
Abbreviations: LEH, liposome-encapsulated hemoglobin; ND, not determined; The data are provided as mean±s.e.m. The heart rate and arterial blood pressure (MAP) were measured at baseline (before induction of hypovolemic shock (HS)), immediately after hypovolemic shock (iHS) and at 6 hours. P-value <0.05 versus Baseline*, iHS¥, HS$, and LEHϕ.