Table 5.
Evaluation of the hepatotoxic effect of the plant extracts on the biochemical parameters with twice daily oral administration in mice
| Control | F. indica | Z hamiense | C. procera | S. imbricata | |
|---|---|---|---|---|---|
| ALT | 290.1 ± 54.0 | 350.2 ± 113.6 | 155.3 ± 65.5 | 211.0 ± 35.8 | 253.3 ± 24.0 |
| AST | 850.0 ± 63.2 | 800.0 ± 235.8 | 520.3 ± 220.0 | 404.2 ± 37.2b | 653.3 ± 78.8 |
| ALP | 180.0 ± 20.3 | 113.3 ± 16.7a | 105.6 ± 15.4a | 98.2 ± 9.3b | 60.0 ± 23.1b |
| CAT kU/g protein | 462.0 ± 21.1 | 461.6 ± 14.9 | 428.750 ± 10.3 | 413.950 ± 11.4 | 486.3 ± 18.0 |
| GSH-Px U/g protein | 1.3 ± 0.1 | 1.3 ± 0.05 | 1.3 ± 0.07 | 1.6 ± 0.06 | 1.31 ± 0.14 |
| SOD μg/g protein | 34.6 ± 2.9 | 35.5 ± 2.7 | 32.8 ± 1.1 | 35.5 ± 1.4 | 32.1 ± 1.4 |
| TBARS (nmol/g prot.) | 0.49 ± 0.02 | 0.39 ± .03 | 0.046 ± 0.03 | 0.038 ± 0.02 | 0.035 ± 0.4 |
aSignificant difference (p < 0.05) compared to control group; bSignificant difference (p < 0.01) compared to control group