Table 3. Diffusion parameters in Caco-2 cells monolayers.
Parameter* | Units | Stavudine | Lamivudine | Zidovudine |
---|---|---|---|---|
Papp x10-6 | cm/s | 6.4 ± 1.8 | 7.0 ± 2.0 | 20.3 ± 4.7 |
Flujo (J) | µg/cm2/min | 0.081 ± 0.003 | 0.041 ± 0.005 | 0.063 ± 0.004 |
*Mean ± SD (n= 10)
Papp= Apparent permeability coefficient