Table 2. The genotype and allele frequency of SNP rs3821949 and rs12532 in 300 Chinese Han CHD patients and 400 non-CHD controls.
| SNP | Group | Genotype frequency (%) | Allele frequency (%) | ||||
|---|---|---|---|---|---|---|---|
| rs3821949 | Genotype | G/G | G/A | A/A | G | A | |
| CHD | 300 | 189(63.0) | 74(24.7) | 37(12.3) | 452(75.3) | 148(24.7) | |
| VSD | 128 | 81(63.3) | 31(24.2) | 16(12.5) | 193(75.4) | 63(24.6) | |
| ASD | 107 | 63(58.9) | 29(27.1) | 15(14.0) | 155(72.4) | 59(27.6) | |
| Controls | 400 | 292(73.0) | 72(18.0) | 36(9.0) | 656(82.0) | 144(18.0) | |
| rs12532 | Genotype | G/G | G/A | A/A | G | A | |
| CHD | 300 | 121(40.3) | 139(46.3) | 40(13.3) | 381(63.5) | 219(36.5) | |
| VSD | 128 | 55(43.0) | 62(48.4) | 11(8.6) | 172(67.2) | 84(32.8) | |
| ASD | 107 | 31(29.0) | 64(59.8) | 12(11.2) | 126(58.9) | 88(41.1) | |
| Controls | 400 | 126(31.5) | 219(54.8) | 55(13.8) | 471(58.9) | 329(41.1) | |