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. 2015 Nov 10;10(11):e0142666. doi: 10.1371/journal.pone.0142666

Table 3. SNP rs3821949 and rs12532 within MSX1 gene associated with the risk of congenital heart diseases in Chinese populations.

Title Pearson Chi-square Pearson’s R
Genotyped SNP Disease Type Statistical Types Value Min count a df Asymp. Sig. (2-sided) Value Asymp. Std. error b Approx. T c Approx. Sig
rs3821949 CHD-Control Genotype 7.974 31.29 2 0.019 -0.098 0.038 -2.606 0.009 d
Allele 9.231 125.14 1 0.002 -0.081 0.027 -3.046 0.002 d
VSD-Control Genotype 4.425 12.61 2 0.109 -0.086 0.045 -1.976 0.049 d
Allele 5.376 50.18 1 0.020 -0.071 0.032 -2.322 0.020 d
ASD-Control Genotype 8.029 10.76 2 0.018 -0.118 0.047 -2.661 0.008 d
Allele 9.657 42.84 1 0.002 -0.098 0.034 -3.119 0.002 d
rs12532 CHD-Control Genotype 6.187 40.71 2 0.045 0.069 0.038 1.825 0.068 d
Allele 3.079 234.86 1 0.079 0.047 0.027 1.755 0.079 d
VSD-Control Genotype 6.509 16.00 2 0.039 0.110 0.042 2.536 0.012 d
Allele 5.627 100.12 1 0.018 0.073 0.030 2.376 0.018 d
ASD-Control Genotype 0.972 14.14 2 0.615 0.000 0.043 0.001 0.999 d
Allele 0.000 88.01 1 0.999 0.000 0.031 0.001 0.999 d

a: The minimum expected count

b: Not assuming the null hypothesis

c: Using the asymptotic standard error assuming the null hypothesis

d: Based on normal approximation