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Left: The subunit composition of the BAF complex is shown with the cancers containing frequent mutations in specific BAF subunits. The general pattern that emerges is that specific subunits protect against cancer in specific tissues. Right: The polybromo containing the pBAF complex with known specific subunits: BAF180 (polybromo PBRM1), BAF200 (ARID2), BAF45a (PHF10), and BRD7.
