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Expression of MCP-1 gene following stimulation of mouse islets with single cytokines (A) IL-1β, TNF-α, or IFN-γ at 1x, 2x, or 4x or dual cytokines with (B) IL-1β/TNF-α, IL-1β/IFN-γ, or TNF-α/IFN-γ relative to stimulation with PICs. ## p < 0.01, ### p < 0.001 relative to PIC and n = 3.
