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. 2015 Nov 10;10(11):e0142735. doi: 10.1371/journal.pone.0142735

Fig 5. STA-5326 inhibits PIC-induced IL-12 gene expression in β-cells and improves β-cell survival.

Fig 5

(A) IL-12 p40, (B) IL-12 p35, and (C) IL-23 p19 gene expression in βTC-3 cells treated with PICs in the absence or presence of 100nM STA-5326. (D) Pro-caspase-3 cleavage in PIC-treated βTC-3 cells without or with 1nM or 100nM STA-5326. *** p < 0.001 relative to Ctl, # p < 0.05, ### p < 0.001, #### p < 0.0001 relative to PIC and n = 3.