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Effect of GHRH agonists on the proliferation of rat islets. (A) Proliferation of rat islet cells after 24 h of treatment with MR-356 or MR-409. (B) Relative expression levels of insulin in rat islets treated with 1 μM MR-356 or MR-409 for 48 h. (C and D) Comparison of total IPN and IEQ/IPN in rat islets treated with either 1 μM MR409 or vehicle for 48 h; T-0, islets before culture. **P < 0.01.
