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. 2015 Oct 20;112(44):E6068–E6077. doi: 10.1073/pnas.1519073112

Fig. S2.

Fig. S2.

SRC-2 regulates the expression of Gck and G6pc. (A) qPCR analysis of SRC-2 gene expression in primary hepatocytes transfected with individual or combined siRNAs against SRC-2. (B) qPCR analysis of Gck and G6pc expression in wild-type primary hepatocytes infected with adenovirus expressing GFP, SRC-1, SRC-2, or SRC-3. (C) Glycolytic flux of [U]-13C–labeled glucose in primary hepatocytes isolated from SRC-2WT or SRC-2KO mice. Data are represented as M3-13C–labeled G6pc and pyruvate, respectively (M indicates nominal mass). (D) qPCR analysis of SRC-2 expression in wild-type primary hepatocytes transfected with control siRNA or siSRC-2 in the presence or absence of insulin or forskolin. (E) qPCR analysis of SRC-2 expression in wild-type primary hepatocytes infected with adenovirus expressing GFP or SRC-2 in the presence or absence of insulin or forskolin. Data are graphed as the mean ± SEM. *P < 0.05, **P < 0.01, ***P < 0.001.