Table 1. Correlation between NUSAP1 expression and parameters in OSCCs.
Results of immunostaining | |||||||
---|---|---|---|---|---|---|---|
No. patients | |||||||
Clinical classification | Total | NUSAP1(-) | NUSAP1(+) | p value | |||
Age at surgery (years) | |||||||
<60 | 19 | 7 | (35%) | 12 | (65%) | 0.214 | |
60–70 | 27 | 5 | (17%) | 22 | (83%) | ||
70> | 24 | 4 | (20%) | 20 | (80%) | ||
Gender | |||||||
Male | 40 | 9 | (25%) | 31 | (75%) | 0.512 | |
Female | 30 | 7 | (20%) | 23 | (80%) | ||
T-primary tumor size | |||||||
T1 | 5 | 1 | (20%) | 4 | (80%) | 0.204 | |
T2 | 37 | 12 | (32%) | 25 | (68%) | ||
T3 | 13 | 2 | (10%) | 11 | (90%) | ||
T4 | 15 | 1 | (6%) | 14 | (94%) | ||
T1+T2 | 42 | 13 | (33%) | 29 | (67%) | 0.048* | |
T3+T4 | 28 | 3 | (8%) | 25 | (92%) | ||
N-regional lymph node | |||||||
Negative | 39 | 11 | (25%) | 28 | (75%) | 0.533 | |
Positive | 31 | 5 | (21%) | 26 | (79%) | ||
TNM stage | |||||||
I | 5 | 1 | (20%) | 4 | (80%) | 0.691 | |
II | 25 | 6 | (24%) | 19 | (76%) | ||
III | 21 | 4 | (25%) | 17 | (75%) | ||
IV | 19 | 5 | (21%) | 14 | (79%) | ||
Histopathological type | |||||||
Well-differentiated | 43 | 9 | (21%) | 34 | (79%) | 0.456 | |
Moderately differentiated | 16 | 5 | (36%) | 11 | (64%) | ||
Poorly differentiated | 11 | 2 | (22%) | 9 | (78%) | ||
Tumoral site | |||||||
Gingiva | 15 | 3 | (20%) | 12 | (80%) | 0.552 | |
Tongue | 40 | 10 | (25%) | 30 | (75%) | ||
Buccal mucosa | 6 | 1 | (17%) | 5 | (83%) | ||
Oral floor | 9 | 2 | (22%) | 7 | (78%) | ||
Total | 70 | 16 | 54 |
NUSAP1(-), down-regulated NUSAP1; NUSAP1(+), up-regulated NUSAP1.
*p < 0.05. (χ2 test).