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. 2015 Nov 10;10(11):e0142456. doi: 10.1371/journal.pone.0142456

Fig 2. TAK-242 suppresses cardiac inflammation and fibrosis caused by Aldo-salt in vivo.

Fig 2

(A-C) Cardiac mRNA levels of TNF-α, MCP-1 and IL-1β in rats treated with Aldo-salt or with Aldo-salt plus TAK-242. *p< 0.05 vs control, #p< 0.05 vs Aldo-salt. (D) Cardiac protein levels of TNF-α, MCP-1 and IL-1β in rats treated with Aldo-salt or with Aldo-salt plus TAK-242 were assayed using ELISA. *p< 0.05 vs control, #p< 0.05 vs Aldo-salt.