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. 2015 Nov 10;10(11):e0142456. doi: 10.1371/journal.pone.0142456

Fig 4. Histological findings.

Fig 4

Cardiac (A) or renal (B) mRNA levels of Col I and TGF-β in rats treated with Aldo-salt or with Aldo-salt plus TAK-242. *p< 0.05 vs control, #p< 0.05 vs Aldo-salt. (C)Representative images and quantitation of perivascular fibrosis in left ventricles of rats treated with Aldo-salt or with Aldo-salt plus TAK-242. *p< 0.05 vs control, #p< 0.05 vs Aldo-salt. (D) Histological staining with periodic acid Schiff (PAS), also showing tubulointerstitial damage of rats treated with Aldo-salt or with Aldo-salt plus TAK-242. *p< 0.05 vs control, #p< 0.05 vs Aldo-salt. n = 9, 200× magnification.