Figure 1. Scopolamine increases Fos+ immunoreactivity in the mPFC.
The influence of scopolamine administration (25 µg/kg, i.p.) on Fos+ immunoreactivity in mPFC of rat was determined 1 hr after drug treatment. Shown in the panels to the left are representative images from vehicle and scopolamine treated animals demonstrating induction of Fos+ neurons in the PrL and IL. The number of Fos+ neurons was analyzed and the results are show in the bar graphs to the right for each region. The results are the mean ± S.E.M. of 6 rats per group. * p < 0.01 compared to vehicle (Student’s t-test).