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. Author manuscript; available in PMC: 2016 Dec 1.
Published in final edited form as: Bone. 2015 Sep 5;81:533–543. doi: 10.1016/j.bone.2015.09.003

Figure 4.

Figure 4

Changes in gene expression 7 days after fracture in the OSX-Cre line. The values are normalized to the OSX-Cre control group’s uninjured (left) femora data. (A) Bmp2 is modestly upregulated during fracture repair in both control (Bmp2fl/fl) and cKO (Bmp2fl/fl;OSX-Cre) animals. However, since the baseline expression in knockout animals is approximately half that of control animals, the increase in cKO fractured limbs does not reach the same level as that of fractured controls. (B) Bsp is similarly expressed in both groups’ uninjured limbs. However, the increased expression caused by fracture is blunted in cKO animals. Lines indicate p<0.05 between groups.