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. Author manuscript; available in PMC: 2016 Oct 1.
Published in final edited form as: Neurobiol Dis. 2015 Jun 6;82:152–163. doi: 10.1016/j.nbd.2015.05.020

Figure 8. Scyllo-inositol inhibits Aβ oligomer-induced internalization of synaptic proteins in vivo.

Figure 8

(A) Representative Western blots showing certain membrane proteins in fractions of synaptic plasma membrane (SPM) or post-synaptic density (PSD) isolated from the hippocampus 4 day after ICV injection with synthetic wt Aβ40 or (Aβ40 S26C)2 dimer in the presence or absence of chiro-or scyllo-inositol (20 μM). GAPDH is a control. (B) Bar, average level of synaptic or membrane protein in different conditions normalized to GAPDH. Asterisks indicate data significantly different from those of mice injected with aCSF alone (p < 0.01 by one-way ANOVA test). Data are from 4 independent experiments.