Table 4.

Chemokines and cluster of differentiation mRNAs found in Gjb1^−/Y//Gjc2^−/− cerebella.

The table shows the chemokines and CD genes in Gjb1^−/Y//Gjc2^−/− mice ranked by fold change (FC) based on the levels of detected mRNA, and shows the false discovery rate (FDR), adjusted p value for each mRNA, and the immune cells known to express them.

name	FC	FDR	p	expression by cell type
Ccl6	13	0	0.0002	macrophages and neutrophils (Orlofsky, et al. 1991)
Ccl3	10.	0	0.0002	microglia (Williams, et al. 2014)
Ccl4	7.3	0	0.001	microglia (Williams, et al. 2014)
Ccl9	3.7	0	0.002	macrophages (Williams, et al. 2014)
Cxcl10	2.2	0	0.03	monocytes, chemokine for monocytes/macrophages and T-cells (Williams, et al. 2014)
Cx3cr1	2.2	0	0.003	microglia (Williams, et al. 2014)
Ccl2	1.9	0	0.01	secreted by monocytes/ macrophages, chemokine for macrophages and T-cells (Orlofsky, et al. 1991); Williams et al., 2014)
Cxcl12	1.9	0	0.02	microglia (Williams, et al. 2014)
CD52	6.5	0	0.0002	mature lymphocytes, monocytes (Buggins, et al. 2002, Domagala and Kurpisz 2001)
CD84	3.5	0	0.0006	memory B-cells (Tangye, et al. 2002)
CD68	3.0	0	0.002	macrophages, monocytes (Holness and Simmons 1993)
CD14	2.8	0	0.001	macrophages, monocytes, dendritic cells (Simmons, et al. 1989)
CD72	2.5	0	0.0009	B- and T-cells (Van de Velde, et al. 1991)
CD53	2.5	0	0.002	leukocyte surface glycoproteins (Horejsi and Vlcek 1991)
CD109	2.2	0	0.002	activated T-cells (Sutherland, et al. 1991)
CD86	2.1	0	0.005	antigen presenting cells, costimulating/activating T- cells (Chen, et al. 1994)
CD48	2.0	0	0.009	B- and T-cells (Yokoyama, et al. 1991)
CD37	1.9	0	0.003	leukocyte surface glycoprotein (Horejsi and Vlcek 1991)
CD9	1.6	0	0.004	leukocyte surface glycoprotein (Horejsi and Vlcek 1991)
CD33	1.6	0.2	0.01	myeloid lineage, lymphoid cells (Garnache-Ottou, et al. 2005, Hernandez-Caselles, et al. 2006, Perez-Oliva, et al. 2011)